Pulmonary arterial hypertension and lung transplantation: when one severe pathology is replaced by another

Abstract Pulmonary arterial hypertension (PAH) is a rare and severe disease characterised by the progressive narrowing of small pulmonary arteries resulting in right-sided heart failure. Despite advances treatment, some PAH patients require lung transplantation, which carries risks long-term complications. We report case male patient with no significant comorbidities, who developed dyspnoea on exertion at age 38 years. After echocardiography right catheterisation, he was confirmed idiopathic started treatment bosentan, sildenafil beraprost. 3 years stability, worsened. Treatment continuous intravenous epoprostenol introduced national premiere, unfortunately little effect. The underwent transplantation 43 Afterwards, several complications, including chronic allograft dysfunction, post-transplant lymphoproliferative disorder embolism. He died 52 invasive aspergillosis. noteworthy due to above-average survival despite multiple